Date of Publish: 04/09/2006

Hypersensitivity to titanium: Clinical and laboratory evidence

Muller K, Valentine-Thon E. Neuro Endocrinol Lett 2006; 27(Suppl 1): 31-35
Fifty-six patients who had developed clinical symptoms after receiving titanium-based implants were tested in the MELISA® test against 10 metals including titanium. Out of 56 patients, 54 were patch-tested with titanium as well as with other metals. The implants were removed in 54 patients. Following removal of the implants, all 54 patients showed remarkable clinical improvement.

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